Research Grade Andecaliximab (HB945016)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

100ug
1mg

수량:

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개요
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참고 문헌
데이터시트

개요

카탈로그 번호	HB945016
설명	Andecaliximab (HB945016) is a research-grade recombinant antibody targeting Matrix metalloproteinase-9. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Chimeric
이소타입	IgG4-kappa
발현 시스템	Mammalian Cells
클론성	Monoclonal
타겟	Matrix metalloproteinase-9, CLG4B, GELB, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, MMP9, MMP-9
내독소 수준	Please contact the lab for this information.
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P14780
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
대체 이름	GS-5745, 1518996-49-0
배경	Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-\|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. 1. Takino, T. et al. (2003) Oncogene 22, 4617-26. PMID: 12879005 2. Tschesche, H. et al. (1992) Matrix (Stuttgart, Germany). Supplement 1, 245-55. PMID: 1480034 3. Wilhelm, SM. et al. (1989) The Journal of biological chemistry 264, 17213-21. PMID: 2551898 4. Jeon, S. et al. (2020) Circulation 142, 1736-1751. PMID: 32883094
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

SEC-HPLC

SEC-HPLC detection for Research Grade Andecaliximab.
Bioactivity

Detects MMP9 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Andecaliximab.

참고 문헌

데이터시트

Research Grade Andecaliximab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Research Grade Andecaliximab (HB945016)

개요

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참고 문헌

데이터시트

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