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Research Grade Tefibazumab (JN060016)

Research Grade Tefibazumab
Research Grade Tefibazumab
Research Grade Tefibazumab
Research Grade Tefibazumab
가격(USD): $
사양:
  • 100ug
  • 1mg
수량:
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  • 개요

  • 이미지

  • 참고 문헌

  • 데이터시트

개요
카탈로그 번호JN060016
설명
Tefibazumab (JN060016) is a research-grade recombinant antibody targeting clfAClumping factor A. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성Staphylococcus aureus
응용 분야ELISA, Functional assay, Research in vivo
숙주 종Humanized
이소타입IgG1-kappa
발현 시스템 Mammalian Cells
클론성 Monoclonal
타겟 clfA Clumping factor A
내독소 수준 Please contact the lab for this information.
순도 >95% purity as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 Q53653, Q2G015, Q5HHM8
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
대체 이름Aurexis, 521079-87-8
배경

Clumping factor A (clfAClumping factor A) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.

참고사항 For research use only. Not suitable for clinical or therapeutic use.
이미지
  • Research Grade Tefibazumab

    Bioactivity

    SEC-HPLC detection for Research Grade Tefibazumab.

  • Research Grade Tefibazumab

    SDS-PAGE

    SDS-PAGE for Research Grade Tefibazumab.

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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