Research Grade Anti-Human CD4 (Campath-9H) (HF998013)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

20ug
50ug
100ug
1mg

수량:

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개요
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참고 문헌
데이터시트

개요

카탈로그 번호

HF998013

설명

Anti-Human CD4 (Campath-9H) (HF998013) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

숙주 종

Humanized

이소타입

IgG1-kappa

클론 ID

Campath-9H

발현 시스템

Mammalian Cells

클론성

Monoclonal

타겟

T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4

내독소 수준

Please contact the lab for this information.

순도

>95% purity as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P01730

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

배경

T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

참고사항

For research use only. Not suitable for clinical or therapeutic use.

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