



| 카탈로그 번호 | HB941016 |
|---|---|
| 설명 |
Ranibizumab (HB941016) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Humanized |
| 이소타입 | Fab-G1-kappa |
| 발현 시스템 | Mammalian Cells |
| 클론성 | Monoclonal |
| 타겟 | Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A |
| 내독소 수준 | Please contact the lab for this information. |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein L purified from cell culture supernatant. |
| 등록번호 | P15692 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 대체 이름 | Fab-12variantY0317, RhuFab, 347396-82-1 |
| 배경 | Vascular endothelial growth factor A, long form (VEGFA) is a ~43 kDa protein. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A. Involved in protecting cells from hypoxia-mediated cell death. VEGFA is the therapeutic target of bevacizumab (Avastin). 1. Katsman, M. et al. (2022) Cells 11. PMID: 35455969 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |

Detects Human VEGFA in indirect ELISAs.

SDS-PAGE for Research Grade Ranibizumab.




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