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Research Grade Ranibizumab (HB941016)

Research Grade Ranibizumab
Research Grade Ranibizumab
Research Grade Ranibizumab
Research Grade Ranibizumab
가격(USD): $
사양:
  • 100ug
  • 1mg
수량:
문의하기
  • 개요

  • 이미지

  • 참고 문헌

  • 데이터시트

개요
카탈로그 번호HB941016
설명
Ranibizumab (HB941016) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성Human
응용 분야ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종Humanized
이소타입Fab-G1-kappa
발현 시스템 Mammalian Cells
클론성 Monoclonal
타겟 Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A
내독소 수준 Please contact the lab for this information.
순도 >95% purity as determined by SDS-PAGE.
정제 Protein L purified from cell culture supernatant.
등록번호 P15692
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
대체 이름Fab-12variantY0317, RhuFab, 347396-82-1
배경

Vascular endothelial growth factor A, long form (VEGFA) is a ~43 kDa protein. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A. Involved in protecting cells from hypoxia-mediated cell death. VEGFA is the therapeutic target of bevacizumab (Avastin).

1. Katsman, M. et al. (2022) Cells 11. PMID: 35455969
참고사항 For research use only. Not suitable for clinical or therapeutic use.
이미지
  • Research Grade Ranibizumab

    Bioactivity

    Detects Human VEGFA in indirect ELISAs.

  • Research Grade Ranibizumab

    SDS-PAGE

    SDS-PAGE for Research Grade Ranibizumab.

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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