Research Grade Anti-Human CD155/PVR Antibody (Ntx1088) (HB135026)

데이터시트 제품 공유 정보 복사

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사양:

100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트

개요

카탈로그 번호	HB135026
설명	Anti-Human CD155/PVR Antibody (Ntx1088) (HB135026) is a research-grade recombinant antibody targeting CD155. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
이소타입	IgG4-kappa
클론 ID	Ntx1088
발현 시스템	Mammalian Cells
타겟	Nectin-like protein 5 receptor, CD155, PVR, PVS, NECL-5
내독소 수준	Please contact the lab for this information.
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P15151
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
대체 이름	Ntx1088, Ntx1088, Ntx-1088
배경	Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell.
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD155/PVR Antibody (Ntx1088)
Bioactivity

Detects recombinant human CD155/PVR (Catalog No: HB135011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human CD155 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD155 monoclonal antibody (Catalog HB135026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.