Research Grade Clazakizumab (HY328056)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

100ug
1mg

수량:

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개요
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참고 문헌
데이터시트

개요

카탈로그 번호	HY328056
설명	Research Grade Clazakizumab (HY328056) is a humanized monoclonal antibody detecting Hybridoma growth factor in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Humanized
이소타입	IgG1-kappa
발현 시스템	Mammalian Cells
종	Human
클론성	Monoclonal
타겟	Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P05231
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
대체 이름	ALD-518, BMS-945429, 1236278-28-6
배경	Interleukin-6 (Hybridoma growth factor,BSF-2,IFN-beta-2,CDF,IL6,Interleukin-6,IL-6,B-cell stimulatory factor 2,Interferon beta-2,IFNB2,CTL differentiation factor) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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SEC-HPLC

SEC-HPLC detection for Research Grade Clazakizumab.
Bioactivity

Detects Human IL6 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Clazakizumab
Western blot

Western blot analysis was performed using anti-IL6 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL6 (Catalog No: HY328021)
Lane 2: negative control