Research Grade Arcitumomab (HY546013)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

20ug
50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트

개요

카탈로그 번호

HY546013

설명

Arcitumomab (HY546013) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

숙주 종

Mouse

이소타입

IgG2a

발현 시스템

Mammalian Cells

클론성

Monoclonal

타겟

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

내독소 수준

Please contact the lab for this information.

순도

>95% purity as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P06731

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

대체 이름

CEA-Scan, IMMU-4, 154361-48-5

배경

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933

2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050

3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308

참고사항

For research use only. Not suitable for clinical or therapeutic use.

이미지

Bioactivity

Detects Human CD66e/CEA/CEACAM5 in direct ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Arcitumomab.

참고 문헌

데이터시트

Research Grade Arcitumomab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Research Grade Arcitumomab (HY546013)

개요

이미지

참고 문헌

데이터시트

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