







| 카탈로그 번호 | HB102016 |
|---|---|
| 설명 |
Gatipotuzumab (HB102016) is a research-grade recombinant antibody targeting CD227. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Humanized |
| 이소타입 | IgG1-kappa |
| 발현 시스템 | Mammalian Cells |
| 클론성 | Monoclonal |
| 타겟 | PEMT, CA 15-3, H23AG, Peanut-reactive urinary mucin, PEM, EMA, Cancer antigen 15-3, MUC-1, Episialin, MUC1-CT, MUC1-beta, Tumor-associated mucin, CD227, Polymorphic epithelial mucin, KL-6, MUC1-alpha, MUC1, PUM, Krebs von den Lungen-6, MUC1-NT, Tumor-associated epithelial membrane antigen, Mucin-1, Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin |
| 내독소 수준 | Please contact the lab for this information. |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P15941 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 대체 이름 | PankoMab, PankoMab-GEX, hPankoMab, 1264737-26-9 |
| 배경 | Mucin-1 (CD227/MUC1) is a ~122 kDa protein. The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Gatipotuzumab.

Flow-cytometry using APC anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Flow-cytometry using FITC anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Flow-cytometry using PE anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.








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