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Recombinant Human CD273/PD-L2/PDCD1LG2 Protein, C-Fc (HV809021)

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사양:
  • 50ug
  • 100ug
  • 1mg
수량:
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  • 개요

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개요
카탈로그 번호HV809021
설명
Recombinant Human CD273/PD-L2/PDCD1LG2 Protein, C-Fc (HV809021) expressed in Mammalian Cells, spanning Met1-Thr220. Purity: >90% by SDS-PAGE.
Highlights
  • Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • Mammalian Expression — Proper folding and native glycosylation.
  • High Purity — >90% purity verified by SDS-PAGE.
발현 시스템Mammalian Cells
등록번호Q9BQ51
단백질 길이Met1-Thr220
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Homo sapiens (Human)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
예측 분자량 51.24 kDa
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2
배경

Programmed cell death 1 ligand 2 is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.

1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527
2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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