Mouse LGMN Recombinant Protein (N-His) (MV606022)

Name: Mouse LGMN Recombinant Protein (N-His)
Brand: abinScience
SKU: MV606022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MV606022
Description	Recombinant Mouse LGMN Protein, N-His (MV606022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O89017
Longueur de protéine	Lys30-Tyr435
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	EC:3.4.22.34, Legumain, Lgmn, Protease, cysteine 1, Prsc1
Contexte	Legumain is a ~49 kDa protein. Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. 1. Zhao, L. et al. (2014) Cell research 24, 344-58. PMID: 24407422 2. Chen, JM. et al. (1998) The Biochemical journal 335 ( Pt 1), 111-7. PMID: 9742219 3. Chen, JM. et al. (1998) FEBS letters 441, 361-5. PMID: 9891971 4. Rodríguez-Silvestre, P. et al. (2023) Science (New York, N.Y.) 380, 1258-1265. PMID: 37347855 5. Morita, Y. et al. (2007) FEBS letters 581, 1417-24. PMID: 17350006 6. Miller, G. et al. (2011) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25, 1606-17. PMID: 21292981
Note	For research use only

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Mouse LGMN Recombinant Protein (N-His).pdf

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