GMP Grade Human IL-3 (Tag Free) (HY262022)

Name: GMP Grade Human IL-3 (Tag Free)
Brand: abinScience
SKU: HY262022
Price: 420 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

50ug
100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	HY262022
Описание	GMP Grade Human IL-3 (Tag Free) (HY262022) expressed in E. coli. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE. Highlights ●Recombinant — Consistent lot-to-lot performance. ●High Purity — >95% as determined by SDS-PAGE. by SDS-PAGE for demanding downstream applications. ●Bioactive — Verified biological activity.
Система экспрессии	E. coli
Номер доступа	P08700
Длина белка	Ala20-Phe152
Применения	ELISA, Functional assay
Виды	Homo sapiens (Human)
Биологическая активность	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.02-0.1 ng/mL.
Характер	Recombinant
Уровень эндотоксинов	<0.01 EU/ug
Чистота	>95% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	15.1 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a 0.22 μm-filtered solution containing 10 mM PB, 5% Mannitol, 0.01% Tween 80, pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Hematopoietic growth factor, IL-3, IL3, Interleukin-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor
Фон	Interleukin-3 (IL3) is a ~17 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB. 1. Guba, SC. et al. (1989) The Journal of clinical investigation 84, 1701-6. PMID: 2556442 2. Okayama, Y. et al. (1993) Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 23, 901-10. PMID: 10779277 3. Hong, L. et al. (2020) Cytokine 136, 155268. PMID: 32889153 4. Luo, XJ. et al. (2012) PloS one 7, e50375. PMID: 23226269 5. Khapli, SM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 142-51. PMID: 12816992 6. Broughton, SE. et al. (2018) Nature communications 9, 386. PMID: 29374162 7. López, C. et al. (2017) Journal of cellular biochemistry 118, 1330-1340. PMID: 27862234
Примечание	For research use only

Изображения

Ссылки

Даташит

GMP Grade Human IL-3 (Tag Free).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

GMP Grade Human IL-3 (Tag Free) (HY262022)

Обзор

Изображения

Ссылки

Даташит

SDS