InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1) (MB199010)

Name: InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1)
Brand: abinScience
SKU: MB199010
Price: 370 USD
Availability: InStock

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Уведомление · Каталог MB199010 был прекращен.

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100ug
1mg

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Каталожный номер	MB199010
Описание	InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1) (MB199010) is a armenian hamster monoclonal antibody detecting CD40 Ligand/TNFSF5 in ELISA, in vivo study. Suitable for Mouse. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Реактивность видов	Mouse
Применения	in vivo blocking of CD40/CD40L signaling, in vitro blocking of CD40/CD40L signaling, WB
Хозяинский вид	Armenian Hamster
Клоональность	Monoclonal
Изотип	IgG, kappa
ID клона	MR-1
Цель	CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, sCD40L, CD40LG, CD40L, TNFSF5
Уровень эндотоксинов	< 1 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P27548
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	CD40 ligand (CD154/CD40L) is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Graf, D. et al. (1992) European journal of immunology 22, 3191-4. PMID: 1280226 2. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 3. Blotta, MH. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 156, 3133-40. PMID: 8617933 4. Mikolajczak, SA. et al. (2004) The Journal of experimental medicine 199, 1025-31. PMID: 15067037
Примечание	For research use only

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InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1).pdf

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