Research Grade Obrindatamab (HV612046)

データシート製品共有情報コピー

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100ug
1mg

数量:

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概要
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参考文献
データシート

概要

カタログ番号	HV612046
説明	Obrindatamab (HV612046) is a research-grade recombinant antibody targeting CD276. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Humanized
アイソタイプ	scFv with Domain Crossover, Kappa;Lambda
発現システム	Mammalian Cells
クローン性	Monoclonal
ターゲット	CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
エンドトキシンレベル	Please contact the lab for this information.
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q5ZPR3 & P07766
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名	Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2
背景	Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer.
注意事項	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Obrindatamab
Bioactivity

Detects CD276 in indirect ELISAs.
Bioactivity

Detects CD3E in indirect ELISAs.
Bioactivity

Detects CD276 in indirect ELISA.
Bioactivity

Detects Recombinant Human CD276 Protein, C-His (Cat No.: HV612011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD276 (Catalog No: HV612011)
Lane 2: negative control

参考文献

HV612046-SDS-PAGE-1.jpg

データシート

Research Grade Obrindatamab.pdf

Formula

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Research Grade Obrindatamab (HV612046)

概要

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参考文献

データシート

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