Anti-ABCC4 Polyclonal Antibody (HT434014)

Name: Anti-ABCC4 Polyclonal Antibody
Brand: abinScience
SKU: HT434014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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SDS

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Número de catálogo

HT434014

Descripción

Anti-ABCC4 Polyclonal Antibody (HT434014) is a rabbit polyclonal antibody detecting ABCC4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ABCC4 (Ile1041-Gln1274).

Objetivo

MOAT-B, MOATB, Multi-specific organic anion transporter B, ATP-binding cassette sub-family C member 4, Multidrug resistance-associated protein 4, MRP4, ABCC4, MRP/cMOAT-related ABC transporter

Purificación

Purified by antigen affinity column.

Número de acceso

O15439

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

ATP-binding cassette sub-family C member 4 (ABCC4) is a ~149 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH).

1. van Aubel, RAMH. et al. (2002) Journal of the American Society of Nephrology : JASN 13, 595-603. PMID: 11856762

2. Zelcer, N. et al. (2003) The Biochemical journal 371, 361-7. PMID: 12523936

3. Sauna, ZE. et al. (2004) The Journal of biological chemistry 279, 48855-64. PMID: 15364914

4. Zhu, Y. et al. (2024) FEBS letters 598, 1967-1980. PMID: 38886124

5. Xie, Z. et al. (2025) Cell reports 44, 115466. PMID: 40138312

6. Reid, G. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 9244-9. PMID: 12835412

7. Rius, M. et al. (2003) Hepatology (Baltimore, Md.) 38, 374-84. PMID: 12883481

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-ABCC4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-ABCC4 Polyclonal Antibody (HT434014)

Vista general

Imágenes

Referencias

Datasheet

SDS