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| カタログ番号 | HW651014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ACVRL1/ALK-1 Polyclonal Antibody (HW651014) is a rabbit polyclonal antibody detecting ACVRL1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ACVRL1/ALK-1 (Asp22-Gln118). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | Serine/threonine-protein kinase receptor R3, SKR3, 2.7.11.30, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, ACVRLK1, ALK1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P37023 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Activin receptor type-1-like (ACVRL1/ALK-1) is a ~56 kDa protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-ACVRL1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
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