

| Каталожный номер | HF594014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-APOC3 Polyclonal Antibody (HF594014) is a rabbit polyclonal antibody detecting APOC3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human APOC3 (Ser21-Ala99). | ||||||||
| Цель | APOC3, Apolipoprotein C3, Apo-CIII, Apolipoprotein C-III, ApoC-III | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P02656 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Apolipoprotein C-III (APOC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. 1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179 2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806 3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013 | ||||||||
| Примечание | For research use only. |



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