InVivoMAb Anti-Human APOC3 Antibody (Iv0249) (HF594010)

Name: InVivoMAb Anti-Human APOC3 Antibody (Iv0249)
Brand: abinScience
SKU: HF594010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	HF594010
Description	InVivoMAb Anti-Human ApoC3 Antibody (Iv0249) [Iv0249] (HF594010) is a human monoclonal antibody detecting Apolipoprotein C-III in ELISA, FuncS. Suitable for Human.
Species reactivity	Human
Applications	ELISA, FuncS
Host species	Human
Isotype	IgG1, kappa
Clone ID	Iv0249
Clonality	Monoclonal
Target	Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3, APOC3
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	P02656
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Apolipoprotein C-III (ApoC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. 1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179 2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806 3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013
Note	For research use only. Not suitable for clinical or therapeutic use.