Anti-APOC3 Polyclonal Antibody (HF594014)

Name: Anti-APOC3 Polyclonal Antibody
Brand: abinScience
SKU: HF594014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF594014

Description

Anti-APOC3 Polyclonal Antibody (HF594014) is a rabbit polyclonal antibody detecting APOC3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human APOC3 (Ser21-Ala99).

Target

APOC3, Apolipoprotein C3, Apo-CIII, Apolipoprotein C-III, ApoC-III

Purification

Purified by antigen affinity column.

Accession

P02656

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Apolipoprotein C-III (APOC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.

1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179

2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806

3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-APOC3 polyclonal antibody at 1ug/mL on recombinant APOC3 (Catalog No. HF594012).

References

Datasheet

Anti-APOC3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-APOC3 Polyclonal Antibody (HF594014)

Overview

Images

References

Datasheet

SDS

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