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Anti-ARG2 Polyclonal Antibody (HX072014)

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Anti-ARG2 Polyclonal Antibody
Anti-ARG2 Polyclonal Antibody
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Vista general
Número de catálogoHX072014
Descripción
Anti-ARG2 Polyclonal Antibody (HX072014) is a rabbit polyclonal antibody detecting ARG2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ARG2 (Val23-Ile354).
Objetivo Arginase-2, mitochondrial, Type II arginase, Kidney-type arginase, Arginase II, Non-hepatic arginase, ARG2
Purificación Purified by antigen affinity column.
Número de acceso P78540
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Arginase-2, mitochondrial (ARG2/Arginase II) is a ~38 kDa protein. May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium.

1. Geiger, R. et al. (2016) Cell 167, 829-842.e13. PMID: 27745970
2. Xu, W. et al. (2016) The Journal of clinical investigation 126, 2465-81. PMID: 27214549
3. McGovern, N. et al. (2017) Nature 546, 662-666. PMID: 28614294
4. Yepuri, G. et al. (2012) Aging cell 11, 1005-16. PMID: 22928666
5. Xiong, Y. et al. (2014) Autophagy 10, 2223-38. PMID: 25484082
6. Xiong, Y. et al. (2013) Journal of the American Heart Association 2, e000096. PMID: 23832324
7. Cama, E. et al. (2003) Biochemistry 42, 8445-51. PMID: 12859189
Nota For research use only.
Imágenes
  • Anti-ARG2 Polyclonal Antibody

    Western blot

    Lane 1: K562 cell lysate
    Lane 2: 293T cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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