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| カタログ番号 | VK490014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ASFV g5Rp/D250R Polyclonal Antibody (VK490014) is a rabbit polyclonal antibody detecting D250R in ELISA, IHC, WB.
Highlights
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| 種反応性 | African swine fever virus (ASFV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant ASFV g5Rp/D250R (Met1-His250). | ||||||||
| ターゲット | mRNA-decapping protein g5R, g5Rp, 3.1.3.-, ASFV-DP, Diphosphoinositol polyphosphate phosphohydrolase, DIPP, 3.6.1.52, Ba71V-102, D250R | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P32092 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | mRNA-decapping protein g5R (g5Rp/D250R) is a ~29 kDa protein. Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis. In addition to the mRNA cap, g5R also efficiently hydrolyzes diphosphoinositol polyphosphates. Down-regulation of the level of PP-InsP5 (diphosphoinositol pentakisphosphate) may play a role in viral manipulation of the cellular secretory pathway, a step necessary for the formation of virions. 1. Parrish, S. et al. (2009) Virology 393, 177-82. PMID: 19695654 2. Quintas, A. et al. (2017) Journal of virology 91. PMID: 29021398 3. Cartwright, JL. et al. (2002) Journal of virology 76, 1415-21. PMID: 11773415 | ||||||||
| 注意事項 | For research use only. |
Lane 1: recombinant ASFV g5Rp/D250R (Catalog No: VK490012)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
