Anti-Bacillus anthracis pagA/Protective antigen Recombinant Nanobody (SAA1225) (JN898013)

Name: Anti-Bacillus anthracis pagA/Protective antigen Recombinant Nanobody (SAA1225)
Brand: abinScience
SKU: JN898013
Price: 126 USD
Availability: InStock

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Especificación:

20ug
50ug
100ug
1mg

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Vista general
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Referencias
Datasheet
SDS

Vista general

Número de catálogo

JN898013

Descripción

Anti-Bacillus anthracis PA/pagA/PA-83 Nanobody (SAA1225) [SAA1225] (JN898013) is a alpaca monoclonal antibody detecting PA-83 in ELISA. Suitable for Bacillus anthracis.

Reactividad de especies

Bacillus anthracis

Aplicaciones

ELISA

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-8His-Cys-tag

ID de clon

SAA1225

Objetivo

Protective antigen, PA, Anthrax toxins translocating protein, PA-83, PA83, Protective antigen PA-20, PA-20, PA20, Protective antigen PA-63, PA-63, PA63, pagA, pag, pXO1-110, BXA0164, GBAA_pXO1_0164

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column.

Número de acceso

P13423

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Protective antigen (PA/pagA) is a ~85 kDa protein. Protective antigen constitutes one of the three proteins composing the anthrax toxin; it mediates attachment to host cells and translocation of edema factor (EF) and lethal factor (LF) into the host cytoplasm. PA associated with LF forms the lethal toxin (LeTx) and causes death when injected; PA associated with EF forms the edema toxin (EdTx) and produces edema. PA induces immunity to infection with anthrax.

1. Bradley, KA. et al. (2001) Nature 414, 225-9. PMID: 11700562

2. Bradley, KA. et al. (2003) The Journal of biological chemistry 278, 49342-7. PMID: 14507921

3. Santelli, E. et al. (2004) Nature 430, 905-8. PMID: 15243628

4. Lacy, DB. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 13147-51. PMID: 15326297

5. Singh, Y. et al. (1991) The Journal of biological chemistry 266, 15493-7. PMID: 1651334

6. Mock, M. et al. (2001) Annual review of microbiology 55, 647-71. PMID: 11544370

Nota

For research use only.

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