Anti-BRAF Polyclonal Antibody (HB617014)

Name: Anti-BRAF Polyclonal Antibody
Brand: abinScience
SKU: HB617014
Price: 96 USD
Availability: InStock

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Vista general

Número de catálogo

HB617014

Descripción

Anti-BRAF Polyclonal Antibody (HB617014) is a rabbit polyclonal antibody detecting BRAF in ELISA, IHC, WB. Suitable for Coturnix japonica, Chicken, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human BRAF (Asn500-His766).

Objetivo

BRAF1, RAFB1, Proto-oncogene B-Raf, BRAF, v-Raf murine sarcoma viral oncogene homolog B1, p94, Serine/threonine-protein kinase B-raf

Purificación

Purified by antigen affinity column.

Número de acceso

P15056

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Serine/threonine-protein kinase B-raf (BRAF) is a ~84 kDa protein. Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. Phosphorylates PFKFB2. May play a role in the postsynaptic responses of hippocampal neurons.

1. Brennan, DF. et al. (2011) Nature 472, 366-9. PMID: 21441910

2. Lavoie, H. et al. (2018) Nature 554, 549-553. PMID: 29433126

3. McGrail, K. et al. (2022) Nature communications 13, 7113. PMID: 36402789

4. Stephens, RM. et al. (1992) Molecular and cellular biology 12, 3733-42. PMID: 1508179

Nota

For research use only.

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