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| カタログ番号 | HB617014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-BRAF Polyclonal Antibody (HB617014) is a rabbit polyclonal antibody detecting BRAF in ELISA, IHC, WB. Suitable for Coturnix japonica, Chicken, Human, and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human BRAF (Asn500-His766). | ||||||||
| ターゲット | BRAF1, RAFB1, Proto-oncogene B-Raf, BRAF, v-Raf murine sarcoma viral oncogene homolog B1, p94, Serine/threonine-protein kinase B-raf | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P15056 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Serine/threonine-protein kinase B-raf (BRAF) is a ~84 kDa protein. Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. Phosphorylates PFKFB2. May play a role in the postsynaptic responses of hippocampal neurons. 1. Brennan, DF. et al. (2011) Nature 472, 366-9. PMID: 21441910 2. Lavoie, H. et al. (2018) Nature 554, 549-553. PMID: 29433126 3. McGrail, K. et al. (2022) Nature communications 13, 7113. PMID: 36402789 4. Stephens, RM. et al. (1992) Molecular and cellular biology 12, 3733-42. PMID: 1508179 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-BRAF polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
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