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Anti-CALM1 Polyclonal Antibody (HY390014)

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Número de catálogoHY390014
Descripción
Anti-CALM1 Polyclonal Antibody (HY390014) is a rabbit polyclonal antibody detecting CALM1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Achlya klebsiana, and Agaricus bisporus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CALM1 (Ala2-Lys149).
Objetivo CAM1, CALM1, CAM, CALM, Calmodulin-1
Purificación Purified by antigen affinity column.
Número de acceso P0DP23
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Calmodulin-1 (CALM1) is a ~16 kDa protein. Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels.

1. Tsang, WY. et al. (2006) Molecular biology of the cell 17, 3423-34. PMID: 16760425
2. Reichow, SL. et al. (2013) Nature structural & molecular biology 20, 1085-92. PMID: 23893133
3. Boczek, NJ. et al. (2016) Circulation. Cardiovascular genetics 9, 136-146. PMID: 26969752
4. Yu, CC. et al. (2016) Heart rhythm 13, 1716-23. PMID: 27165696
5. Zhao, YG. et al. (2017) Molecular cell 67, 974-989.e6. PMID: 28890335
6. Wren, LM. et al. (2019) Circulation. Genomic and precision medicine 12, 375-385. PMID: 31454269
7. Alphonse, N. et al. (2022) Cell 185, 2354-2369.e17. PMID: 35568036
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-CALM1 Polyclonal Antibody

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