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Anti-CCHFV Glycoprotein Gn Polyclonal Antibody (VK608014)

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Aperçu
Numéro de catalogueVK608014
Description
Anti-CCHFV GP/Envelope glycoprotein Polyclonal Antibody (VK608014) is a rabbit polyclonal antibody detecting Glycoprotein N in ELISA, IHC, WB.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesCrimean-Congo hemorrhagic fever virus (CCHFV)
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant CCHFV GP/Envelope glycoprotein (Ser520-Ser698).
Cible Envelopment polyprotein, M polyprotein, Mucin-like variable region, GP38, Glycoprotein N, Gn, 37 kDa protein, Glycoprotein G2, Non-Structural protein M, NSm, 15 kDa protein, Glycoprotein C, Gc, 75 kDa protein, Glycoprotein G1, GP
Purification Purified by antigen affinity column.
Numéro d'accès Q8JSZ3
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Envelopment polyprotein (GP/Envelope glycoprotein) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state.

1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887
2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291
3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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