Anti-CCHFV Gc Polyclonal Antibody (VK608034)

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Overview

Catalog No.

VK608034

Description

Anti-CCHFV Gc Polyclonal Antibody (VK608034) is a rabbit polyclonal antibody detecting CCHFV Gc in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Crimean-Congo hemorrhagic fever virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant CCHFV Gc (Phe1041-Asn1594).

Target

Glycoprotein C, Gc, 75 kDa protein, Glycoprotein G1, GP

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q8JSZ3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Gc) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state.

1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887

2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291

3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197

Note

For research use only

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Datasheet