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| カタログ番号 | VK608014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CCHFV GP/Envelope glycoprotein Polyclonal Antibody (VK608014) is a rabbit polyclonal antibody detecting Glycoprotein N in ELISA, IHC, WB.
Highlights
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| 種反応性 | Crimean-Congo hemorrhagic fever virus (CCHFV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant CCHFV GP/Envelope glycoprotein (Ser520-Ser698). | ||||||||
| ターゲット | Envelopment polyprotein, M polyprotein, Mucin-like variable region, GP38, Glycoprotein N, Gn, 37 kDa protein, Glycoprotein G2, Non-Structural protein M, NSm, 15 kDa protein, Glycoprotein C, Gc, 75 kDa protein, Glycoprotein G1, GP | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8JSZ3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Envelopment polyprotein (GP/Envelope glycoprotein) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state. 1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887 2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291 3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197 | ||||||||
| 注意事項 | For research use only. |
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