

| Каталожный номер | HW589014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-CD144/CDH5 Polyclonal Antibody (HW589014) is a rabbit polyclonal antibody detecting CD144 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CD144/CDH5 (Val68-Thr307). | ||||||||
| Цель | 7B4 antigen, CD144, VE-cadherin, Cadherin-5, CDH5, Vascular endothelial cadherin | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P33151 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Cadherin-5 (CD144/CDH5) is a ~87 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1. 1. Brasch, J. et al. (2011) Journal of molecular biology 408, 57-73. PMID: 21269602 2. Shimoyama, Y. et al. (2000) The Biochemical journal 349, 159-67. PMID: 10861224 3. Lampugnani, MG. et al. (2010) Journal of cell science 123, 1073-80. PMID: 20332120 4. Abiko, H. et al. (2015) Journal of cell science 128, 1683-95. PMID: 25795300 | ||||||||
| Примечание | For research use only. |




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