Anti-Human CD144/CDH5/VE-cadherin Recombinant Antibody (SAA1971) (HW589013)

Name: Anti-Human CD144/CDH5/VE-cadherin Recombinant Antibody (SAA1971)
Brand: abinScience
SKU: HW589013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW589013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1971

Clonality

Monoclonal

Target

7B4 antigen, CD144, VE-cadherin, Cadherin-5, CDH5, Vascular endothelial cadherin

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P33151

RRID

Anti-Human CD144/CDH5/VE-cadherin Antibody (SAA1971) (abinScience Cat# HW589013, RRID:AB_3727735)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Cadherin-5 (CD144/CDH5) is a ~87 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1.

1. Brasch, J. et al. (2011) Journal of molecular biology 408, 57-73. PMID: 21269602

2. Shimoyama, Y. et al. (2000) The Biochemical journal 349, 159-67. PMID: 10861224

3. Lampugnani, MG. et al. (2010) Journal of cell science 123, 1073-80. PMID: 20332120

4. Abiko, H. et al. (2015) Journal of cell science 128, 1683-95. PMID: 25795300

Note

For research use only.

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