

| Numéro de catalogue | HC579014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CD213a2/IL13RA2 Polyclonal Antibody (HC579014) is a rabbit polyclonal antibody detecting CD213a2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CD213a2/IL13RA2 (Pro238-Glu334). | ||||||||
| Cible | IL13R, IL-13RA2, IL-13 receptor subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL-13R subunit alpha-2, IL13RA2, Interleukin-13 receptor subunit alpha-2 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q14627 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Interleukin-13 receptor subunit alpha-2 (CD213a2/IL13RA2) is a ~44 kDa protein. Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. 1. Rahaman, SO. et al. (2002) Cancer research 62, 1103-9. PMID: 11861389 2. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 3. Fichtner-Feigl, S. et al. (2006) Nature medicine 12, 99-106. PMID: 16327802 | ||||||||
| Note | For research use only. |




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