Anti-Human CD282/TLR2 Polyclonal Antibody (HT188014)

Name: Anti-Human CD282/TLR2 Polyclonal Antibody
Brand: abinScience
SKU: HT188014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HT188014

Описание

Anti-CD282/TLR2 Polyclonal Antibody (HT188014) is a rabbit polyclonal antibody detecting CD282 in ELISA, IHC, WB. Suitable for Human, Macaca fascicularis, Macaca mulatta, Pan paniscus, and Pan troglodytes.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CD282/TLR2 (Glu21-Leu590).

Цель

TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

O60603

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

1. Jin, MS. et al. (2007) Cell 130, 1071-82. PMID: 17889651

2. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852

3. Brightbill, HD. et al. (1999) Science (New York, N.Y.) 285, 732-6. PMID: 10426995

4. Aliprantis, AO. et al. (1999) Science (New York, N.Y.) 285, 736-9. PMID: 10426996

5. Bulut, Y. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 987-94. PMID: 11441107

6. Jung, SB. et al. (2006) Infection and immunity 74, 2686-96. PMID: 16622205

7. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712

8. Bulut, Y. et al. (2005) The Journal of biological chemistry 280, 20961-7. PMID: 15809303

9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human CD282/TLR2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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