Anti-Integrin beta 1/CD29 Recombinant Antibody (AIIB2) (HY248307)

Name: Anti-Integrin beta 1/CD29 Recombinant Antibody (AIIB2)
Brand: abinScience
SKU: HY248307
Price: 191 USD
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Número de catálogo	HY248307
Reactividad de especies	Human
Aplicaciones	ELISA, FCM, FuncS, ICC, IF, IHC, IP, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	AIIB2
Objetivo	CD29, FNRB, Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, ITGB1, Integrin beta-1, MDF2, MSK12, VLA-4 subunit beta
Nivel de endotoxinas	<10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P05556
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Integrin beta-1 (CD29/ITGB1) is a ~88 kDa protein. Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099 3. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 4. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 5. Bax, DV. et al. (2003) The Journal of biological chemistry 278, 34605-16. PMID: 12807887 6. Jovanovic, J. et al. (2007) The Journal of biological chemistry 282, 6743-51. PMID: 17158881 7. Schumacher, S. et al. (2021) Science advances 7. PMID: 33962943 8. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430 9. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 10. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
Nota	For research use only