Anti-CD322/JAM2 Polyclonal Antibody (HX993014)

Name: Anti-CD322/JAM2 Polyclonal Antibody
Brand: abinScience
SKU: HX993014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HX993014

Описание

Anti-CD322/JAM2 Polyclonal Antibody (HX993014) is a rabbit polyclonal antibody detecting CD322 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CD322/JAM2 (Tyr74-Val250).

Цель

JAM-B, VEJAM, Junctional adhesion molecule B, JAM2, VE-JAM, JAM-2, C21orf43, Vascular endothelial junction-associated molecule, Junctional adhesion molecule 2, CD322

Очистка

Purified by antigen affinity column.

Номер доступа

P57087

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Junctional adhesion molecule B (CD322/JAM2) is a ~33 kDa protein. Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM3 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating not only transmigration but also tethering and rolling of leukocytes along the endothelium. Tethering and rolling of leukocytes are dependent on the binding by JAM2 of the integrin alpha-4/beta-1.

1. Arrate, MP. et al. (2001) The Journal of biological chemistry 276, 45826-32. PMID: 11590146

2. Liang, TW. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 1618-26. PMID: 11823489

3. Arcangeli, ML. et al. (2014) Stem cells (Dayton, Ohio) 32, 1043-54. PMID: 24357068

4. Johnson-Léger, CA. et al. (2002) Blood 100, 2479-86. PMID: 12239159

5. Cunningham, SA. et al. (2002) The Journal of biological chemistry 277, 27589-92. PMID: 12070135

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-CD322/JAM2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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