Anti-Human N-Cadherin Polyclonal Antibody (HB862014)

Name: Anti-Human N-Cadherin Polyclonal Antibody
Brand: abinScience
SKU: HB862014
Price: 96 USD
Availability: InStock

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Vista general

Número de catálogo

HB862014

Descripción

Anti-Human N-Cadherin Polyclonal Antibody (HB862014) is a rabbit polyclonal antibody detecting N-Cadherin in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CD325/CDH2 (Asp160-Ala724).

Aplicaciones probadas

Objetivo

N-cadherin, CDH2, Cadherin-2, CD325, CDw325, Neural cadherin, CDHN, NCAD

Purificación

Purified by antigen affinity column.

Número de acceso

P19022

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Cadherin-2 (CD325/CDH2) is a ~99 kDa protein. Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching.

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-CDH2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
Lane 3: Rat brain lysate