

| Catalog No. | HB862207 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG2a |
| Clone ID | A14 |
| Clonality | Monoclonal |
| Target | N-cadherin, CDH2, Cadherin-2, CD325, CDw325, Neural cadherin, CDHN, NCAD |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P19022 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Cadherin-2 (CD325/CDH2) is a ~99 kDa protein. Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching. |
| Note | For research use only. |

SDS-PAGE for Anti-Human CD325/CDH2 Antibody (A14)




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