Anti-Human N-Cadherin Polyclonal Antibody (HB862014)

Name: Anti-Human N-Cadherin Polyclonal Antibody
Brand: abinScience
SKU: HB862014
Price: 96 USD
Availability: InStock

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Каталожный номер

HB862014

Описание

Anti-Human N-Cadherin Polyclonal Antibody (HB862014) is a rabbit polyclonal antibody detecting N-Cadherin in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CD325/CDH2 (Asp160-Ala724).

Проверенные приложения

Цель

N-cadherin, CDH2, Cadherin-2, CD325, CDw325, Neural cadherin, CDHN, NCAD

Очистка

Purified by antigen affinity column.

Номер доступа

P19022

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Cadherin-2 (CD325/CDH2) is a ~99 kDa protein. Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching.

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-CDH2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
Lane 3: Rat brain lysate