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| カタログ番号 | HB797014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CD6 Polyclonal Antibody (HB797014) is a rabbit polyclonal antibody detecting CD6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD6 (His18-Cys350). | ||||||||
| ターゲット | TP120, CD6, T12, T-cell differentiation antigen CD6 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P30203 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | T-cell differentiation antigen CD6 is a ~71 kDa protein. Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. 1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703 2. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938 3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806 4. Hassan, NJ. et al. (2006) Molecular and cellular biology 26, 6727-38. PMID: 16914752 5. Roncagalli, R. et al. (2014) Nature immunology 15, 384-392. PMID: 24584089 6. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728 | ||||||||
| 注意事項 | For research use only. |
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