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| カタログ番号 | HC475014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CD91/LRP1 Polyclonal Antibody (HC475014) is a rabbit polyclonal antibody detecting LRP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD91/LRP1 (Ala20-His280). | ||||||||
| ターゲット | APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q07954 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. 1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044 2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657 3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392 4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438 5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178 6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553 7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371 | ||||||||
| 注意事項 | For research use only. |
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