Anti-Human CD91/LRP1 Recombinant Antibody (SAA1580) (HC475013)

Name: Anti-Human CD91/LRP1 Recombinant Antibody (SAA1580)
Brand: abinScience
SKU: HC475013
Price: 196 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC475013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1580

Clonality

Monoclonal

Target

APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q07954

RRID

Anti-Human CD91/LRP1 Antibody (SAA1580) (abinScience Cat# HC475013, RRID:AB_3727341)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor.

1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044

2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657

3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392

4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438

5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178

6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553

7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD91/LRP1 Antibody (SAA1580)

References

Datasheet

Anti-Human CD91/LRP1 Recombinant Antibody (SAA1580).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD91/LRP1 Recombinant Antibody (SAA1580) (HC475013)

Overview

Images

References

Datasheet

SDS

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