Anti-Human Clusterin Polyclonal Antibody (HY453014)

Name: Anti-Human Clusterin Polyclonal Antibody
Brand: abinScience
SKU: HY453014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

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SDS

Aperçu

Numéro de catalogue

HY453014

Description

Anti-CLU Polyclonal Antibody (HY453014) is a rabbit polyclonal antibody detecting CLU in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CLU (Ser228-Glu449).

Cible

APOJ, ApoJalpha, NA1/NA2, Complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Ku70-binding protein 1, Testosterone-repressed prostate message 2, ApoJbeta, TRPM-2, Complement cytolysis inhibitor b chain, SGP-2, KUB1, Apolipoprotein J, Apo-J, Clusterin, Sulfated glycoprotein 2, Aging-associated gene 4 protein, CLI, CLU, Complement-associated protein SP-40, 40

Purification

Purified by antigen affinity column.

Numéro d'accès

P10909

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Clusterin (APOJ/SP-40) is a ~52 kDa protein. Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70.

1. Poon, S. et al. (2000) Biochemistry 39, 15953-60. PMID: 11123922

2. Wyatt, AR. et al. (2009) The Journal of biological chemistry 284, 21920-21927. PMID: 19535339

3. Poon, S. et al. (2002) The Journal of biological chemistry 277, 39532-40. PMID: 12176985

4. Stewart, EM. et al. (2007) Biochemistry 46, 1412-22. PMID: 17260971

5. Wyatt, AR. et al. (2010) The Journal of biological chemistry 285, 3532-3539. PMID: 19996109

6. Hatters, DM. et al. (2002) European journal of biochemistry 269, 2789-94. PMID: 12047389

7. Kumita, JR. et al. (2007) Journal of molecular biology 369, 157-67. PMID: 17407782

8. Yerbury, JJ. et al. (2007) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 2312-22. PMID: 17412999

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human Clusterin Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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Kits d'Essai

Anti-Human Clusterin Polyclonal Antibody (HY453014)

Aperçu

Images

Reférences

Fiche technique

SDS