

| Número de catálogo | HT160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CPLX1 Polyclonal Antibody (HT160014) is a rabbit polyclonal antibody detecting CPLX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CPLX1 (Met1-Lys134). | ||||||||
| Objetivo | Complexin-1, CPLX1, CPX I, Synaphin-2, Complexin I | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O14810 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Complexin-1 (CPLX1) is a ~15 kDa protein. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. 1. Kümmel, D. et al. (2011) Nature structural & molecular biology 18, 927-33. PMID: 21785414 | ||||||||
| Nota | For research use only. |



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