Anti-Human CPLX1 Polyclonal Antibody (HT160024)

Name: Anti-Human CPLX1 Polyclonal Antibody
Brand: abinScience
SKU: HT160024
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HT160024

Description

Anti-Human CPLX1 Polyclonal Antibody (HT160024) is a rabbit polyclonal antibody detecting CPLX1 in ELISA, IHC, WB. Suitable for Macaca fascicularis, Mus musculus, Narke japonica, Human, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CPLX1 (Met1-Lys134).

Target

CPLX1

Purification

Purified by antigen affinity column.

Accession

O14810

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1

Background

Complexin-1 (CPLX1) is a ~15 kDa protein. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

1. Kümmel, D. et al. (2011) Nature structural & molecular biology 18, 927-33. PMID: 21785414

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CPLX1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat cerebellum lysate