

| Numéro de catalogue | HT160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CPLX1 Polyclonal Antibody (HT160014) is a rabbit polyclonal antibody detecting CPLX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CPLX1 (Met1-Lys134). | ||||||||
| Cible | Complexin-1, CPLX1, CPX I, Synaphin-2, Complexin I | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O14810 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Complexin-1 (CPLX1) is a ~15 kDa protein. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. 1. Kümmel, D. et al. (2011) Nature structural & molecular biology 18, 927-33. PMID: 21785414 | ||||||||
| Note | For research use only. |



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