Anti-CREB1 Polyclonal Antibody (HB851014)

Name: Anti-CREB1 Polyclonal Antibody
Brand: abinScience
SKU: HB851014
Price: 168 USD
Availability: InStock

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Каталожный номер

HB851014

Описание

Anti-CREB1 Polyclonal Antibody (HB851014) is a rabbit polyclonal antibody detecting CREB1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CREB1 (Lys122-Asp327).

Цель

cAMP-responsive element-binding protein 1, CREB-1, CREB1, Cyclic AMP-responsive element-binding protein 1

Очистка

Purified by antigen affinity column.

Номер доступа

P16220

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Cyclic AMP-responsive element-binding protein 1 (CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling.

1. Conkright, MD. et al. (2003) Molecular cell 12, 413-23. PMID: 14536081

Примечание

For research use only.

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