

| Catalog No. | HB851013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | IHC, IP, WB | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA0304 | ||||
| Clonality | Monoclonal | ||||
| Target | cAMP-responsive element-binding protein 1, CREB-1, CREB1, Cyclic AMP-responsive element-binding protein 1 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P16220 | ||||
| RRID | Anti-Phospho-CREB1 (pS133) Antibody (SAA0304) (abinScience Cat# HB851013, RRID:AB_3725765) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Cyclic AMP-responsive element-binding protein 1 (p-CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling. 1. Conkright, MD. et al. (2003) Molecular cell 12, 413-23. PMID: 14536081 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Phospho-CREB1 (pS133) Antibody (SAA0304)



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