

| Каталожный номер | HC693014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-DGKZ Polyclonal Antibody (HC693014) is a rabbit polyclonal antibody detecting DGKZ in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human DGKZ (Gly411-Lys624). | ||||||||
| Цель | DAGK6, DAG kinase zeta, Diglyceride kinase zeta, DGK-zeta, Diacylglycerol kinase zeta, DGKZ | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q13574 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Diacylglycerol kinase zeta (DGKZ) is a ~103 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Does not exhibit an acyl chain-dependent substrate specificity among diacylglycerol species. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro but less efficiently and with a preference for alkylacylglycerols containing an arachidonoyl group. 1. Epand, RM. et al. (2004) Biochemistry 43, 14778-83. PMID: 15544348 2. Epand, RM. et al. (2007) Biochemistry 46, 14225-31. PMID: 18004883 3. Lung, M. et al. (2009) The Journal of biological chemistry 284, 31062-73. PMID: 19744926 4. Shulga, YV. et al. (2011) FEBS letters 585, 4025-8. PMID: 22108654 5. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129 6. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 7. Ding, L. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5519-24. PMID: 9159104 | ||||||||
| Примечание | For research use only. |




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