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Anti-DLL4 Polyclonal Antibody (HV571014)

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Vista general
Número de catálogoHV571014
Descripción
Anti-DLL4 Polyclonal Antibody (HV571014) is a rabbit polyclonal antibody detecting DLL4 in ELISA, IHC, WB. Suitable for Human and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human DLL4 (Leu16-Ala539).
Objetivo Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
Purificación Purified by antigen affinity column.
Número de acceso Q9NR61
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.

1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954
2. Brütsch, R. et al. (2010) Circulation research 107, 592-601. PMID: 20616313
3. Del Barrio, MG. et al. (2007) Development (Cambridge, England) 134, 3427-36. PMID: 17728344
Nota For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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