Anti-DLL4 Polyclonal Antibody (HV571014)

Name: Anti-DLL4 Polyclonal Antibody
Brand: abinScience
SKU: HV571014
Price: 168 USD
Availability: InStock

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Aperçu

Numéro de catalogue

HV571014

Description

Anti-DLL4 Polyclonal Antibody (HV571014) is a rabbit polyclonal antibody detecting DLL4 in ELISA, IHC, WB. Suitable for Human and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human DLL4 (Leu16-Ala539).

Cible

Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9NR61

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.

1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954

2. Brütsch, R. et al. (2010) Circulation research 107, 592-601. PMID: 20616313

3. Del Barrio, MG. et al. (2007) Development (Cambridge, England) 134, 3427-36. PMID: 17728344

Note

For research use only.

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