Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody (VK536014)

Name: Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody
Brand: abinScience
SKU: VK536014
Price: 168 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

VK536014

Описание

Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody (VK536014) is a rabbit polyclonal antibody detecting BZLF1 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Epstein-Barr virus (HHV-4) (Human herpesvirus 4)

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant EBV/HHV-4 BZLF1 (Leu175-Phe245).

Цель

Lytic switch protein BZLF1, EB1, Protein Z, Trans-activator protein BZLF1, Zta, bZIP transcription factor ZEBRA, BZLF1

Очистка

Purified by antigen affinity column.

Номер доступа

P03206

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Lytic switch protein BZLF1 is a ~26 kDa protein. Transcription factor that acts as a molecular switch to induce the transition from the latent to the lytic or productive phase of the virus cycle (Probable). Mediates the switch from the latent to the lytic cycle of infection in cells containing a highly methylated viral genome. Probably binds to silenced chromatin and recruits host chromatin-remodeling enzymes. Regulates this switch by binding to 2 types of ZEBRA response elements (ZREs): the CpG-free AP-1 like elements (latency) and the methylated CpG-containing elements (lytic replication) (Probable). Activates preferentially the methylated forms of the viral lytic R (BRLF1) and Na (BRRF1) gene promoters, the latters being the first genes activated during Z-mediated reactivation in latently infected cells.

1. Schepers, A. et al. (1993) The EMBO journal 12, 3921-9. PMID: 8404860

2. Bhende, PM. et al. (2004) Nature genetics 36, 1099-104. PMID: 15361873

3. Bernaudat, F. et al. (2022) Nucleic acids research 50, 490-511. PMID: 34893887

4. Schaeffner, M. et al. (2019) Life science alliance 2. PMID: 30926617

5. Flower, K. et al. (2011) PloS one 6, e25922. PMID: 22022468

6. Dickerson, SJ. et al. (2009) PLoS pathogens 5, e1000356. PMID: 19325883

7. Feederle, R. et al. (2000) The EMBO journal 19, 3080-9. PMID: 10856251

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-BLZF1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant EBV/HHV-4 BZLF1 (Catalog No: VK536012)

Ссылки

Даташит

Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа