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Anti-Eculizumab ELISA Kit (AF687018)

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Vista general
Número de catálogoAF687018
Descripción
Anti-Eculizumab ELISA Kit (AF687018) — Quantitative sandwich ELISA for Anti-Eculizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL.
Highlights
  • ●Sandwich Format — High specificity, reliable quantification.
  • ●Ready-to-Use — Complete kit with pre-coated plates included.
Tipo de muestraPlasma, Serum
Rango156.25 - 10, 000 ng/mL
Número de acceso P01031
Aplicaciones ELISA
Método de detección Colorimetric
Tipo de ensayo Quantitative
Recuperación 80-120%
Envío 2-8 ℃
Estabilidad y almacenamiento The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Especificaciones

Eculizumab

Nombres alternativos5G1.1, h5G1.1HuG2/G4, 219685-50-4
Fondo

Complement C5 (Eculizumab) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586
2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047
3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019
4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279
5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456
6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882
Nota For Research Use Only.
Imágenes
Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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